ORG-03

E-factor

E = m_waste / m_product. Mass of waste per mass of product.

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Green chemistrySheldon E-factor

Governing equation

E=m_{\mathrm{waste}}/m_{\mathrm{product}}

where

m_{waste}: Waste mass (kg)
m_{product}: Product mass (kg)
E: E-factor (—)

Lecture brief

Historical brief

Hammett (1937) and Taft linear free-energy, E-factor green metrics, Woodward–Fieser UV and Claisen equilibria are how organic chemistry became predictive. The lab is substituent, waste and tautomer. This sheet (ORG-03 — E-factor) is the form associated with Sheldon E-factor. Working symbols: $m_{waste}$ , $m_{product}$ $\rightarrow$ $E$ . Sheldon: bulk chemicals E ~ 1–5, pharmaceuticals often > 25. Water may be excluded by convention.

Purpose

Purpose: compute

E

from

m_{waste}

m_{product}

in Organic chemistry via

E=m_{\mathrm{waste}}/m_{\mathrm{product}}

E = m_waste / m_product. Mass of waste per mass of product. Use it when a real organic chemistry question must be answered in SI before a code check.

Live realistic example

In symbols

Live case. Given

m_{waste} = 12.000\,\mathrm{kg}

m_{product} = 1.500\,\mathrm{kg}

, the governing relation

E=m_{\mathrm{waste}}/m_{\mathrm{product}}

yields

E = 8.00\,\mathrm{—}

. Batch masses, product isolated. Move a slider: the numbers are this situation, not a canned story.

Calculator

Inputs

Waste mass m_{waste}12 kgProduct mass m_{product}1.5 kg

Outputs

E-factor E8.00 —

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Narration of this film

Batch masses, product isolated.

Sheldon: bulk chemicals E ~ 1–5, pharmaceuticals often > 25. Water may be excluded by convention.

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