INGENIA

NMD-04

Percent injected dose

%ID = 100 A_organ / A_inj. Fraction of the injection in an organ.

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Uptake%ID

Governing equation

%ID=100 Aorgan/Ainj\%\mathrm{ID}=100\,A_{\mathrm{organ}}/A_{\mathrm{inj}}

Aorg∈[0.1,400]A_{org} \in \left[0.1, 400\right]

where

A_{org}
Organ activity (MBq)
A_{inj}
Injected activity (MBq)
\%ID
Percent injected dose (%)

The figure, part by part

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NMD-04 · gauge
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①

Governing law — red

%ID=100 Aorgan/Ainj\%\mathrm{ID}=100\,A_{\mathrm{organ}}/A_{\mathrm{inj}}

Aorg∈[0.1,400]A_{org} \in \left[0.1, 400\right]

Aorg=0.1A_{org} = 0.1%ID=0.027\%ID = 0.027

②

Domain of the variable — blue

A_{org}_{\min} = 0.1,\quad A_{org}_{\max} = 400

Aorg∈[0.1,400]A_{org} \in \left[0.1, 400\right]

Aorg=0.1A_{org} = 0.1Aorg=0.1A_{org} = 0.1

③

Response curve — green

%ID=100 Aorgan/Ainj\%\mathrm{ID}=100\,A_{\mathrm{organ}}/A_{\mathrm{inj}}

Aorg∈[0.1,400]A_{org} \in \left[0.1, 400\right]

Aorg=0.1A_{org} = 0.1%ID=0.027\%ID = 0.027

④

Rate of change — amber

d%IDdAorg\frac{\mathrm{d}\%ID}{\mathrm{d}A_{org}}

Aorg∈[0.1,400]A_{org} \in \left[0.1, 400\right]

Aorg=2.615A_{org} = 2.615%ID′=0.27\%ID^{\prime} = 0.27

Lecture brief

Historical brief

MIRD schema, in-vivo decay, uptake fractions and PET coincidence turned unsealed sources into organ dose. The sheets compute activity, residence and well-counter geometry. This sheet (NMD-04 — Percent injected dose) is the form associated with %ID. Working symbols: AorgA_{org}, AinjA_{inj} →\rightarrow %ID\%ID. Decay-correct the organ counts back to injection time before dividing. %ID/g is the density version.

Purpose

Purpose: compute %ID\%ID from AorgA_{org}, AinjA_{inj} in Nuclear medicine via %ID=100 Aorgan/Ainj\%\mathrm{ID}=100\,A_{\mathrm{organ}}/A_{\mathrm{inj}} %ID = 100 A_organ / A_inj. Fraction of the injection in an organ. Use it when a real nuclear medicine question must be answered in SI before a code check.

Live realistic example

In symbols

Live case. Given Aorg=40.000 MBqA_{org} = 40.000\,\mathrm{MBq}, Ainj=370.000 MBqA_{inj} = 370.000\,\mathrm{MBq}, the governing relation %ID=100 Aorgan/Ainj\%\mathrm{ID}=100\,A_{\mathrm{organ}}/A_{\mathrm{inj}} yields \%ID = 10.81\,\mathrm{%}. A syringe, an organ, a percentage. Move a slider: the numbers are this situation, not a canned story.

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Inputs

Outputs

  • Percent injected dose \%ID10.81 %
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Narration of this film

A syringe, an organ, a percentage.

Decay-correct the organ counts back to injection time before dividing. %ID/g is the density version.

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Watch on YouTube