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NMD-01

MIRD absorbed dose

D = Ã S. Cumulated activity times the S-value of the source–target pair.

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Internal dosimetryMIRD

Governing equation

D=A~SD=\tilde A\, S

where

\tilde A
Cumulated activity (MBq·h)
S
S-value (mGy/MBq/h)
D
Absorbed dose (mGy)

Lecture brief

Historical brief

MIRD schema, in-vivo decay, uptake fractions and PET coincidence turned unsealed sources into organ dose. The sheets compute activity, residence and well-counter geometry. This sheet (NMD-01 — MIRD absorbed dose) is the form associated with MIRD. Working symbols: A~\tilde A, SS \rightarrow DD. Ã = ∫A(t) dt. S folds geometry, yield and absorbed fractions into mGy/MBq/h.

Purpose

Purpose: compute DD from A~\tilde A, SS in Nuclear medicine via D=A~SD=\tilde A\, S D = Ã S. Cumulated activity times the S-value of the source–target pair. Use it when a real nuclear medicine question must be answered in SI before a code check.

Live realistic example

In symbols

Live case. Given A~=200.000MBqh\tilde A = 200.000\,\mathrm{MBq·h}, S=0.050mGy/MBq/hS = 0.050\,\mathrm{mGy/MBq/h}, the governing relation D=A~SD=\tilde A\, S yields D=10.00mGyD = 10.00\,\mathrm{mGy}. A source organ, a target, a dose. Move a slider: the numbers are this situation, not a canned story.

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Inputs

Outputs

  • Absorbed dose D10.00 mGy
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NMD-01 · dose
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Narration of this film

A source organ, a target, a dose.

à = ∫A(t) dt. S folds geometry, yield and absorbed fractions into mGy/MBq/h.

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